Yale scientists use nanotechnology to fight E. coli
“The nanotubes are microscopic carbon cylinders, thousands of times smaller than a human hair that can be easily taken up by human cells,” said Elimelech. “We wanted to find out more about where and how they are toxic.” This “nanoscience version of a David-and-Goliath story” was hailed in an ACS preview of the work as the first direct evidence that “carbon nanotubes have powerful antimicrobial activity, a discovery that could help fight the growing problem of antibiotic resistant infections.” Using the simple E. coli as test cells, the researchers incubated cultures of the bacteria in the presence of the nanotubes for up to an hour. The microbes were killed outright – but only when there was direct contact with aggregates of the SWCNTs that touched the bacteria. Elimelech speculates that the long, thin nanotubes puncture the cells and cause cellular damage.
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